Dental Stem Cells

The Mesenchymal Stem Cells found in Teeth are now the most researched Stem Cells in the Scientific Literature.

Dental Stem Cell Research

  1. Li, L, He, Y, Zhao, J, Yin, H, Feng, X, Fan, X et al.. Mesenchymal Stromal Cell-Based Therapy: A Promising Approach for Autoimmune Diseases. Clin Rev Allergy Immunol. 2025;68 (1):21. doi: 10.1007/s12016-025-09030-9. PubMed PMID:39982546 .
  2. Cao, Y, Liu, Z, Xie, Y, Hu, J, Wang, H, Fan, Z et al.. Correction: Adenovirus-mediated transfer of hepatocyte growth factor gene to human dental pulp stem cells under good manufacturing practice improves their potential for periodontal regeneration in swine. Stem Cell Res Ther. 2025;16 (1):73. doi: 10.1186/s13287-025-04214-8. PubMed PMID:39980047 .
  3. Thongsit, A, Oontawee, S, Siriarchavatana, P, Rodprasert, W, Somparn, P, Na Nan, D et al.. Scalable production of anti-inflammatory exosomes from three-dimensional cultures of canine adipose-derived mesenchymal stem cells: production, stability, bioactivity, and safety assessment. BMC Vet Res. 2025;21 (1):81. doi: 10.1186/s12917-025-04517-1. PubMed PMID:39979916 .
  4. Bermudez, A, Latham, ZD, Ma, AJ, Bi, D, Hu, JK, Lin, NYC et al.. Regulation of chromatin modifications through coordination of nucleus size and epithelial cell morphology heterogeneity. Commun Biol. 2025;8 (1):269. doi: 10.1038/s42003-025-07677-w. PubMed PMID:39979587 .
  5. Sadrabad, ZK, Habibivand, E, Samiei, M, Shadkar, MM, Farzi, S. Comparative evaluation of cytotoxic effects of a new biomaterial nanohydroxyapatite-lactoferrin, nanohydroxyapatite, mineral trioxide aggregate, and calcium-enriched mixture on human dental pulp stem cells. J Conserv Dent Endod. 2025;28 (1):57-62. doi: 10.4103/JCDE.JCDE_666_24. PubMed PMID:39974685 PubMed Central PMC11835352.
  6. Liu, JN, Tian, JY, Liu, L, Cao, Y, Lei, X, Zhang, XH et al.. The landscape of cell regulatory and communication networks in the human dental follicle. Front Bioeng Biotechnol. 2025;13 :1535245. doi: 10.3389/fbioe.2025.1535245. PubMed PMID:39974190 PubMed Central PMC11835805.
  7. Fang, X, Gao, S, Li, Y, Xu, K, Huo, Q, Xiao, P et al.. Hypoxia-preconditioned human dental pulp stem cells transplantation alleviates hypoxic-ischemic brain damage via STAT3/NLRP3/Caspase-1 axis in neonatal rats. Neuroreport. 2025; :. doi: 10.1097/WNR.0000000000002144. PubMed PMID:39973887 .
  8. Jia, L, Xiao, H, Hao, Z, Sun, S, Zhao, W, Gong, Z et al.. Senolytic elimination of senescent cells improved periodontal ligament stem cell-based bone regeneration partially through inhibiting YAP. Biochim Biophys Acta Mol Cell Res. 2025;1872 (3):119921. doi: 10.1016/j.bbamcr.2025.119921. PubMed PMID:39971252 .
  9. Abedi, N, Sadeghian, A, Kouhi, M, Haugen, HJ, Savabi, O, Nejatidanesh, F et al.. Immunomodulation in Bone Tissue Engineering: Recent Advancements in Scaffold Design and Biological Modifications for Enhanced Regeneration. ACS Biomater Sci Eng. 2025; :. doi: 10.1021/acsbiomaterials.4c01613. PubMed PMID:39970366 .
  10. Wang, X, Xu, Y, Yu, C, Deng, R, Chen, Y, Jiang, K et al.. Periodontitis-related myocardial fibrosis by expansion of collagen-producing SiglecF+ neutrophils. Eur Heart J. 2025; :. doi: 10.1093/eurheartj/ehaf049. PubMed PMID:39969161 .
  11. Mufidah, N, Muzari, K, Budi, HS, Indrawati, R, Anitasari, S, Shen, YK et al.. Oral anticancer promising of hexadecanoic acid through melecular interaction to nuclear factor-kappa-B p65/RELA and tumor suppressor-p53. Braz J Biol. 2025;85 :e287760. doi: 10.1590/1519-6984.287760. PubMed PMID:39969016 .
  12. Sung, TC, Pan, ZX, Wang, T, Lin, HY, Chang, CL, Hung, LC et al.. Material surface conjugated with fibroblast growth factor-2 for pluripotent stem cell culture and differentiation. Regen Biomater. 2025;12 :rbaf003. doi: 10.1093/rb/rbaf003. PubMed PMID:39967781 PubMed Central PMC11835233.
  13. Wang, X, Dong, S, Dong, Q, Sun, X. Piezo1 Promotes Odontogenic Differentiation of Dental Pulp Stem Cells Under Stress Conditions. Int Dent J. 2025; :. doi: 10.1016/j.identj.2025.01.018. PubMed PMID:39965987 .
  14. Huang, TY, Naruphontjirakul, P, Tseng, SC, Su, WT. Protective effect of conditioned medium derived from melatonin-stimulated stem cells from the apical papilla on glutamate-induced neurotoxicity in PC12 cells. Neuroscience. 2025; :. doi: 10.1016/j.neuroscience.2025.02.031. PubMed PMID:39965741 .
  15. Coelho, LAS, Bordini, EAF, Cassiano, FB, de Toledo Stuani, V, Silva, RM, Dos Passos, DGS et al.. Impact of endodontic irrigant solutions on the viability and metabolism of stem cells from apical papilla: proposal of a novel in vitro model. Clin Oral Investig. 2025;29 (2):136. doi: 10.1007/s00784-025-06231-6. PubMed PMID:39964548 .
  16. Vembuli, H, Rajasingh, S, Nabholz, P, Guenther, J, Morrow, BR, Taylor, MM et al.. Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy. Exp Biol Med (Maywood). 2025;250 :10342. doi: 10.3389/ebm.2025.10342. PubMed PMID:39963344 PubMed Central PMC11830513.
  17. Zhang, H, Zhao, R, Wang, X, Qi, Y, Sandai, D, Wang, W et al.. Interruption of mitochondrial symbiosis is associated with the development of osteoporosis. Front Endocrinol (Lausanne). 2025;16 :1488489. doi: 10.3389/fendo.2025.1488489. PubMed PMID:39963284 PubMed Central PMC11830588.
  18. Zakrzewski, P, Rice, CM, Fleming, K, Cela, D, Groves, SJ, Ponce-Garcia, FM et al.. Tafazzin regulates neutrophil maturation and inflammatory response. EMBO Rep. 2025; :. doi: 10.1038/s44319-025-00393-w. PubMed PMID:39962231 .
  19. Ohshima, H, Ono, K, Mishima, K. Oral biosciences: The annual review 2024. J Oral Biosci. 2025; :100631. doi: 10.1016/j.job.2025.100631. PubMed PMID:39961400 .
  20. Ouchi, T, Shimizu, E, Li, B. Editorial: Perivascular niche and stem cell signaling in tooth. Front Cell Dev Biol. 2025;13 :1555739. doi: 10.3389/fcell.2025.1555739. PubMed PMID:39958889 PubMed Central PMC11825445.
  21. Jafari, N, Seyed Habashi, M, Afshar, A, Ghasemi, M, Kurmanalina, MA, Mussin, NM et al.. The Effect of Exosomes Derived from Human Umbilical Cord Mesenchymal Stromal/Stem Cells on the Regeneration of Human Pulpectomized Tooth: A Case Report. Iran J Med Sci. 2025;50 (1):54-58. doi: 10.30476/ijms.2024.103117.3638. PubMed PMID:39957811 PubMed Central PMC11829066.
  22. Yu, Z, Kawashima, N, Sunada-Nara, K, Wang, S, Han, P, Kieu, TQ et al.. MicroRNA-27a transfected dental pulp stem cells undergo odonto/osteogenic differentiation via targeting DKK3 and SOSTDC1 in Wnt/BMP signaling in vitro and enhance bone formation in vivo. J Transl Med. 2025;23 (1):189. doi: 10.1186/s12967-025-06208-9. PubMed PMID:39956898 PubMed Central PMC11831854.
  23. Jang, M, Yang, J, Jeon, DH, Seung, SH, Lee, G. Potential of human dental pulp stem cell-derived conditioned medium for amelo-/odontoblastic differentiation of HERS/ERM cells. Biochem Biophys Res Commun. 2025;752 :151490. doi: 10.1016/j.bbrc.2025.151490. PubMed PMID:39955953 .
  24. Kim, I, Park, S, Kim, J, Park, SY, Seo, J, Roh, S et al.. Treatment with Lactobacillus paracasei L30 extract induces osteogenic differentiation of human bone marrow mesenchymal stem cells in vitro. Biomed Pharmacother. 2025;184 :117913. doi: 10.1016/j.biopha.2025.117913. PubMed PMID:39955853 .
  25. Liang, B, Chen, X, Sun, Y, Pan, X, Lin, Y, Gao, Q et al.. Dual-functions of prime-and-rinse approach with MDP primer on the performance of modified self-etch adhesive. J Dent. 2025;155 :105629. doi: 10.1016/j.jdent.2025.105629. PubMed PMID:39954803 .
  26. Yang, Y, Yang, P, Zhang, Y, Wu, Z, Wang, X, Zhang, J et al.. LINC00673 binds with leptin to regulate osteogenic function in periodontal ligament stem cells. J Orthop Surg Res. 2025;20 (1):165. doi: 10.1186/s13018-025-05562-0. PubMed PMID:39953568 PubMed Central PMC11827204.
  27. Zhang, S, Song, H, Chang, M, Lu, Y, Liu, S, Wu, J et al.. MSC-EV-transmitted HSPA8 alleviates cisplatin-induced ovotoxicity by regulating the MGARP/PRDX2 axis. Int J Biol Macromol. 2025;304 (Pt 2):140973. doi: 10.1016/j.ijbiomac.2025.140973. PubMed PMID:39952536 .
  28. Desai, SM, Bhonde, RR, Veeranjaneyulu, A, Sanap, A, Jarare, S, Satpute, S et al.. Therapeutic Potential of Mesenchymal Stem Cells or their Secretome in Diabetic Mice with or without Preconditioning Treatment. Recent Adv Inflamm Allergy Drug Discov. 2025; :. doi: 10.2174/0127722708323777250121224618. PubMed PMID:39950288 .
  29. Shojaeian, S, Asnaashari, M, Heidari, A, Sadeghi, M, Mehrabinia, P. Effect of Photodynamic Therapy With Two Different Photosensitizers on the Viability of Human Dental Pulp Stem Cells. J Lasers Med Sci. 2024;15 :e70. doi: 10.34172/jlms.2024.70. PubMed PMID:39949477 PubMed Central PMC11822230.
  30. Kuckelkorn, C, Aksoy, E, Stojanovic, N, Oulahyane, L, Ritter, M, Pfannkuche, K et al.. Engineered In Vitro Multi-Cell Type Ventricle Model Generates Long-Term Pulsatile Flow and Modulates Cardiac Output in Response to Cardioactive Drugs. Adv Healthc Mater. 2025; :e2403897. doi: 10.1002/adhm.202403897. PubMed PMID:39943918 .
  31. Jaksic Karisik, M, Lazarevic, M, Mitic, D, Ajtic, OM, Damante, G, Milasin, J et al.. JQ1 Treatment and miR-21 Silencing Activate Apoptosis of CD44+ Oral Cancer Cells. Int J Mol Sci. 2025;26 (3):. doi: 10.3390/ijms26031241. PubMed PMID:39941011 PubMed Central PMC11818616.
  32. Nikolic, S, Alastra, G, Pultar, F, Lüthy, L, Stadlinger, B, Carreira, EM et al.. Mutanobactin-D, a Streptococcus mutans Non-Ribosomal Cyclic Lipopeptide, Induces Osteogenic/Odontogenic Differentiation of Human Dental Pulp Stem Cells and Human Bone Marrow Stem Cells. Int J Mol Sci. 2025;26 (3):. doi: 10.3390/ijms26031144. PubMed PMID:39940912 PubMed Central PMC11817755.
  33. Kobayashi, T, Hata, M, Sugita, Y, Aoyagi, A, Matsukawa, R, Imanishi, Y et al.. Anodized and hydrothermally treated titanium with a nanotopographic structure combined with dental pulp stem cells promotes bone formation in a rat calvarial bone defect model. J Prosthodont Res. 2025; :. doi: 10.2186/jpr.JPR_D_24_00176. PubMed PMID:39938899 .
  34. Gilat, R, Muth, SA, Hurley, ET, Yazdi, AA, Franzia, CH, Rodeo, SA et al.. Experts Achieve Consensus on a Majority of Statements Regarding Ethics, Transparency, Regulation and Best Practices for the Use of Orthobiologics. Arthroscopy. 2025; :. doi: 10.1016/j.arthro.2025.01.062. PubMed PMID:39938667 .
  35. Cui, A, Ouyang, Z, Xu, C, Wang, C, Rana, Z, Liu, R et al.. Sub-Nanoscale Caffeic Acid-Functionalized TiO2 Composite: Enhancing Mechanical Properties and Odontogenic Differentiation Capacity of Resin-Based Dental Restoration. Small. 2025;21 (6):e2409447. doi: 10.1002/smll.202409447. PubMed PMID:39937514 .
  36. Mazzoldi, EL, Benini, G, Ferraro, RM, Micheletti, M, Martellosio, G, Balduchelli, V et al.. Differentiation of human hyalocytes from induced pluripotent stem cells through ascorbic acid treatment. Hum Cell. 2025;38 (2):52. doi: 10.1007/s13577-025-01182-2. PubMed PMID:39937308 PubMed Central PMC11821750.
  37. Cohen, DJ, Berger, MB, Deng, J, Jacobs, TW, Boyan, BD, Schwartz, Z et al.. Non-Canonical Wnt16 and microRNA-145 Mediate the Response of Human Bone Marrow Stromal Cells to Additively Manufactured Porous 3-Dimensional Biomimetic Titanium-Aluminum-Vanadium Constructs. Cells. 2025;14 (3):. doi: 10.3390/cells14030211. PubMed PMID:39937002 PubMed Central PMC11816670.
  38. Kim, D, Kim, SG. Cell Homing Strategies in Regenerative Endodontic Therapy. Cells. 2025;14 (3):. doi: 10.3390/cells14030201. PubMed PMID:39936992 PubMed Central PMC11817319.
  39. Xiao, L, Shimamura, N, Kamio, T, Ide, R, Mochizuki, M, Nakahara, T et al.. Polycarbonate-Acrylonitrile Butadiene Styrene Three Dimensional Printing Material Exhibits Biocompatibility and Enhances Osteogenesis and Gingival Tissue Formation with Human Cells. Cells. 2025;14 (3):. doi: 10.3390/cells14030167. PubMed PMID:39936959 PubMed Central PMC11816493.
  40. Chen, X, Wang, W, Hu, Y, Sun, J, Zhang, L, Chen, Y et al.. In Situ Assembled Metal-Phenolic Nanozyme Biointerfaces Revitalize Stem Cells and Optimize Diabetic Implant Osseointegration. Adv Healthc Mater. 2025; :e2404804. doi: 10.1002/adhm.202404804. PubMed PMID:39935069 .
  41. Sun, T, Ma, D, Song, Y, Hu, J, Yang, Z, Wang, X et al.. Effects of 0.01 mM strontium on human periodontal ligament stem cell osteogenic differentiation via the Wnt/β-catenin signaling pathway. J Int Med Res. 2025;53 (2):3000605251315024. doi: 10.1177/03000605251315024. PubMed PMID:39932304 PubMed Central PMC11815949.
  42. Zhao, HW, Liu, ST, Wang, XJ, Zhang, XM, Ma, X. Elucidating the Role of HIF-1α/YAP Signaling Pathway in Regulating Inflammation in Human Periodontal Stem Cells: An in vitro Study. J Inflamm Res. 2025;18 :1875-1886. doi: 10.2147/JIR.S504793. PubMed PMID:39931166 PubMed Central PMC11809419.
  43. Liu, L, Chu, Z, Han, X, Wu, J, Cai, K, Wang, J et al.. Creatine promotes osteogenic differentiation of dental pulp stem cells via the AMPK-ULK1-autophagy axis. Connect Tissue Res. 2025; :1-14. doi: 10.1080/03008207.2025.2459243. PubMed PMID:39930963 .
  44. Vallmajo-Martin, Q, Kiveliö, AS, Metzger, S, Milleret, V, Lienemann, PS, Carrara, BM et al.. Undifferentiated Human Amniotic Fluid Progenitor Cells Promote Bone Regeneration in Vivo. Adv Healthc Mater. 2025; :e2300843. doi: 10.1002/adhm.202300843. PubMed PMID:39930929 .
  45. de Souza, JR, Anselmi, C, Cardoso, LM, Kito, LT, Dos Reis-Prado, AH, de Oliveira, PHC et al.. Electrospun SilkMA/silicate-chlorinated cobalt-doped bioactive glass composite for bone regeneration. J Mech Behav Biomed Mater. 2025;164 :106929. doi: 10.1016/j.jmbbm.2025.106929. PubMed PMID:39929130 .
  46. Yumkham, R, Nagarathna, C, Shakuntala, BS, Sarada, R, Yumnam, G, Waikhom, B et al.. Tri-Lineage Differentiation Potential of Stem Cells from Human Exfoliated Deciduous Teeth - An In-vitro Study. J Pharm Bioallied Sci. 2024;16 (Suppl 4):S3364-S3366. doi: 10.4103/jpbs.jpbs_847_24. PubMed PMID:39926977 PubMed Central PMC11804987.
  47. Kaur, T, Khan, N, Pasha, Z, Bhat, R, Virupakshappa, D, Bharisharanesha, R et al.. Stem Cells: Innovations, Applications, and Future Directions. J Pharm Bioallied Sci. 2024;16 (Suppl 4):S3041-S3043. doi: 10.4103/jpbs.jpbs_1089_24. PubMed PMID:39926970 PubMed Central PMC11805146.
  48. Dhevi, GRI, Arangannal, P, Jeevarathan, J. Comparative Analysis of Cytotoxicity and Odontogenic Differentiation of Novel Bioceramic Material on Human Dental Pulp Stem Cells - An In Vitro Study. J Pharm Bioallied Sci. 2024;16 (Suppl 4):S3951-S3955. doi: 10.4103/jpbs.jpbs_1078_24. PubMed PMID:39926897 PubMed Central PMC11805107.
  49. Mori, M, Mori, Y, Nakao, Y, Mandai, S, Fujiki, T, Kikuchi, H et al.. Development of Adult Renal Tubular Organoids from Different Human Individuals in a Single Medium. JMA J. 2025;8 (1):191-197. doi: 10.31662/jmaj.2024-0244. PubMed PMID:39926080 PubMed Central PMC11799510.
  50. Kim, HG, Lee, BN, Jeong, HJ, Kim, HJ, Kwon, J, Oh, S et al.. Effect of Bioactive Glass into Mineral Trioxide Aggregate on the Biocompatibility and Mineralization Potential of Dental Pulp Stem Cells. Biomater Res. 2025;29 :0142. doi: 10.34133/bmr.0142. PubMed PMID:39925797 PubMed Central PMC11803057.
  51. Yang, Y, Huang, J, Hu, X, Jing, M, Zhang, Y, Xu, C et al.. Surface prereacted glass-ionomer particles incorporated into resin composites promote biocompatibility for restoration of subgingival dental defects. Mater Today Bio. 2025;31 :101499. doi: 10.1016/j.mtbio.2025.101499. PubMed PMID:39925721 PubMed Central PMC11803238.
  52. Daghrery, A, Dal-Fabbro, R, Xu, J, Kaigler, D, de Ruijter, M, Gawlitta, D et al.. Niche-inspired collagen infused melt electrowritten scaffolds for craniofacial bone regeneration. Biomater Adv. 2025;170 :214222. doi: 10.1016/j.bioadv.2025.214222. PubMed PMID:39923603 .
  53. Ayoub, KM, Nagy, MM, Aly, RM, El Deen, GN, El-Batouty, K. Effect of Bio MTA plus & ProRoot MTA pulp capping materials on the regenerative properties of human dental pulp stem cells. Sci Rep. 2025;15 (1):4749. doi: 10.1038/s41598-025-88816-5. PubMed PMID:39922901 PubMed Central PMC11807190.
  54. Xu, X, Fu, J, Yang, G, Chen, Z, Chen, S, Yuan, G et al.. Dentin sialoprotein acts as an angiogenic factor through association with the membrane receptor endoglin. J Biol Chem. 2025; :108279. doi: 10.1016/j.jbc.2025.108279. PubMed PMID:39922489 .
  55. Wang, M, Wu, Z, Zheng, X, Huang, Y, Jin, Y, Song, J et al.. Betaine enhances SCAPs chondrogenic differentiation and promotes cartilage repair in TMJOA through WDR81. Stem Cell Res Ther. 2025;16 (1):55. doi: 10.1186/s13287-025-04161-4. PubMed PMID:39920811 PubMed Central PMC11806766.
  56. Zhao, T, Zhong, Q, Sun, Z, Yu, X, Sun, T, An, Z et al.. Decoding SFRP2 progenitors in sustaining tooth growth at single-cell resolution. Stem Cell Res Ther. 2025;16 (1):58. doi: 10.1186/s13287-025-04190-z. PubMed PMID:39920788 PubMed Central PMC11806734.
  57. Peng, Y, Yuan, Q, Zhou, S, Gan, J, Shen, Z, Xia, X et al.. FAK mediates mechanical signaling to maintain epithelial homeostasis through YAP/TAZ-TEADs. Histochem Cell Biol. 2025;163 (1):31. doi: 10.1007/s00418-025-02360-x. PubMed PMID:39918604 .
  58. Murugaiyan, K, Chandramouli, A, Rangasamy, J. Whitlockite nanoparticles incorporated chitin-poly(dioxanone) composite scaffold for alveolar bone regeneration. J Biomater Sci Polym Ed. 2025; :1-17. doi: 10.1080/09205063.2025.2460377. PubMed PMID:39916573 .
  59. Noohi, P, Abdekhodaie, MJ, Nekoofar, MH, Gama, M, Saadatmand, M, Dummer, PMH et al.. Development of Antimicrobial Peptide-loaded Hydrogels as Potential Scaffolds for Pulp-dentine Complex Regeneration: A Comparative Study. J Endod. 2025; :. doi: 10.1016/j.joen.2025.01.018. PubMed PMID:39914769 .
  60. Abdel-Sater, KA. Testosterone in long-term sedentary aging males: Effect of antiaging strategies. Physiol Int. 2025; :. doi: 10.1556/2060.2024.00486. PubMed PMID:39912854 .
  61. Salgado, CL, Cochis, A, Varoni, EM, Mendes, RA. Editorial: The expanding Frontiers of stem cells therapy in oral maxillo-facial engineering and regenerative medicine. Front Bioeng Biotechnol. 2025;13 :1548950. doi: 10.3389/fbioe.2025.1548950. PubMed PMID:39912112 PubMed Central PMC11794199.
  62. Entezami, S, Sam, MR. The role of mesenchymal stem cells-derived from oral and teeth in regenerative and reconstructive medicine. Tissue Cell. 2025;93 :102766. doi: 10.1016/j.tice.2025.102766. PubMed PMID:39908767 .
  63. Khoshbin, E, Karkehabadi, H, Salehi, R, Farmany, A, Najafi, R, Abbasi, R et al.. Comparative study of nanohydroxyapatite-emdogain effects on apical papilla stem cell survival and differentiation. Biotechnol Lett. 2025;47 (1):24. doi: 10.1007/s10529-024-03557-1. PubMed PMID:39907710 .
  64. Wang, C, Mao, Z, Gomchok, D, Li, X, Liu, H, Shao, J et al.. Small extracellular vesicles derived from miRNA-486 overexpressed dental pulp stem cells mitigate high altitude pulmonary edema through PTEN/PI3K/AKT/eNOS pathway. Heliyon. 2025;11 (2):e41960. doi: 10.1016/j.heliyon.2025.e41960. PubMed PMID:39906863 PubMed Central PMC11791212.
  65. Cheng, D, Bao, Y, Wang, X, Xiang, H, Guo, T, Du, Y et al.. WNT3A promotes the cementogenic differentiation of dental pulp stem cells through the FOXO1 signaling pathway. Eur J Med Res. 2025;30 (1):68. doi: 10.1186/s40001-024-02259-8. PubMed PMID:39905528 PubMed Central PMC11792666.
  66. Zhan, P, Huang, Z, Xie, Z, Zhang, X, Shen, Z, Chen, L et al.. FoxO1 mediates odontoblast differentiation of hDPSCs via B cell-derived ANGPTL1 in dental caries: A laboratory investigation. Int Endod J. 2025; :. doi: 10.1111/iej.14206. PubMed PMID:39904951 .
  67. Mutlu Özçınar, B, Özükoç, C, Türkmen, E, Çakır, R. Dental pulp stem cells (DPSCs), stem cells from human exfoliated deciduous teeth (SHEDSCs), and periodontal ligament stem cells (PDLSCs) isolation, characterization and the effectiveness of allantoin as bioactive molecule for dental regeneration. J Dent. 2025;154 :105604. doi: 10.1016/j.jdent.2025.105604. PubMed PMID:39904472 .
  68. Yang, L, Liu, L, Zhang, P, Pan, W, Huang, H, Qi, Y et al.. Rigid and soft substrates respectively promote the myocardial differentiation and maturation of human embryonic stem cells using elastic PDMS with thick synthetic coating. Colloids Surf B Biointerfaces. 2025;250 :114540. doi: 10.1016/j.colsurfb.2025.114540. PubMed PMID:39904141 .
  69. Capalbo, S, Polyakova, A, El Imane, Z, Khan, I, Kawai, T, Shindo, S et al.. A Comprehensive Review of Contemporary Bioreactors for Vascular Inflammation Studies. Inflammation. 2025; :. doi: 10.1007/s10753-024-02231-y. PubMed PMID:39903422 .
  70. Rajasekar, V, Abdalla, MM, Basbrain, MS, Neelakantan, P, Yiu, CK. Odontogenic differentiation of dental pulp stem cells by glycogen synthase kinase-3β inhibitory peptides. Stem Cell Res Ther. 2025;16 (1):34. doi: 10.1186/s13287-025-04150-7. PubMed PMID:39901291 PubMed Central PMC11792195.
  71. Khalil, HF, Metwalli, NEED, Magdy, S, Shamel, M. Tissue-friendly dentin treatments as a potential element in revascularization protocol (ex-vivo study). BMC Oral Health. 2025;25 (1):184. doi: 10.1186/s12903-025-05550-0. PubMed PMID:39901104 PubMed Central PMC11789321.
  72. Gul, MT, Khattak, MNK, Qaisar, R, Jayakumar, MN, Samsudin, ABR, Khan, AA et al.. The Effects of miR-22-3p on Differentiation of Human Dental Pulp Stem Cells into Neural Progenitor-Like Cells. Mol Neurobiol. 2025; :. doi: 10.1007/s12035-025-04702-1. PubMed PMID:39900772 .
  73. Kavakebian, F, Rezapour, A, Seyedebrahimi, R, Eslami Farsani, M, Jabbari Fakhr, M, Zare Jalise, S et al.. Intrinsic and extrinsic modulators of human dental pulp stem cells: advancing strategies for tissue engineering applications. Mol Biol Rep. 2025;52 (1):190. doi: 10.1007/s11033-025-10281-0. PubMed PMID:39899148 .
  74. Guo, X, Huang, Z, Wu, F, Jiang, W, Li, Y, Wang, T et al.. Exosomes of human adipose stem cells mitigate irradiation injury to salivary glands by inhibiting epithelial-mesenchymal transition through miR-199a-3p targeting Twist1 and regulating TGFβ1/Smad3 pathway. Theranostics. 2025;15 (5):1622-1641. doi: 10.7150/thno.102346. PubMed PMID:39897544 PubMed Central PMC11780531.
  75. Zhang, L, Li, X, Zhang, B, Li, R. Extracellular Vesicles in Periodontitis: Pathogenic Mechanisms and Therapeutic Potential. J Inflamm Res. 2025;18 :1317-1331. doi: 10.2147/JIR.S504612. PubMed PMID:39897520 PubMed Central PMC11786598.
  76. Ali, SA, Mahmood, Z, Mubarak, Z, Asad, M, Sarfraz Chaudhri, MT, Bilal, L et al.. Assessing the Potential Benefits of Stem Cell Therapy in Cardiac Regeneration for Patients With Ischemic Heart Disease. Cureus. 2025;17 (1):e76770. doi: 10.7759/cureus.76770. PubMed PMID:39897258 PubMed Central PMC11786102.
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