Dental Stem Cells

The Mesenchymal Stem Cells found in Teeth are now the most researched Stem Cells in the Scientific Literature.

Dental Stem Cell Research

  1. Suzuki, R, Ide, K, Tokuchi, S, Kawano, T, Ntege, EH, Murahashi, M et al.. Selective effects of collagen-derived peptides Pro-Hyp and Hyp-Gly on the proliferation and differentiation of SSEA3-positive human dental pulp stem cells. Regen Ther. 2025;29 :162-170. doi: 10.1016/j.reth.2025.03.003. PubMed PMID:40170801 PubMed Central PMC11960528.
  2. Li, X, Zhao, S, Liu, Y, Gu, Y, Qiu, L, Chen, X et al.. Electric field promoted odontogenic differentiation of stem cells from apical papilla by remodelling cytoskeleton. Int Endod J. 2025; :. doi: 10.1111/iej.14213. PubMed PMID:40170340 .
  3. Sultan, NA, Hamama, HH, Grawish, ME, El-Toukhy, RI, Mahmoud, SH. Impact of different capping materials extracts on proliferation and osteogenic differentiation of cultured human dental pulp stem cells. Sci Rep. 2025;15 (1):11140. doi: 10.1038/s41598-025-93759-y. PubMed PMID:40169700 .
  4. Zhou, Y, Li, M, Lin, S, Zhu, Z, Zhuang, Z, Cui, S et al.. Mechanical sensing protein PIEZO1 controls osteoarthritis via glycolysis mediated mesenchymal stem cells-Th17 cells crosstalk. Cell Death Dis. 2025;16 (1):231. doi: 10.1038/s41419-025-07577-1. PubMed PMID:40169556 .
  5. Oura, Y, Ishii, M, Miyata, H, Ikeda, N, Sakurai, T, Suehiro, F et al.. Evaluation of the effect of platelet-derived growth factor-BB on the biological activity of human mandibular bone marrow-derived mesenchymal stem cells. Arch Oral Biol. 2025;174 :106244. doi: 10.1016/j.archoralbio.2025.106244. PubMed PMID:40168781 .
  6. Ye, L, Li, H, Zhang, W, Zhou, Y, Lan, X, Wang, Y et al.. Blue light-emitting diode promotes mineralization of stem cells from the apical papilla via cryptochrome 1/Wnt/β-catenin signaling. J Mol Histol. 2025;56 (2):125. doi: 10.1007/s10735-025-10400-y. PubMed PMID:40167571 .
  7. Tang, H, Yu, Y, Zhan, X, Wang, F, Xiang, D, Zheng, Y et al.. Zinc-Cobalt Bimetallic Organic Frameworks with Antioxidative and Osteogenic Activities for Periodontitis Treatment. Small. 2025; :e2412065. doi: 10.1002/smll.202412065. PubMed PMID:40167516 .
  8. Liu, G, Xue, J, Zhou, X, Gui, M, Xia, R, Zhang, Y et al.. The paradigm shifts of periodontal regeneration strategy: From reparative manipulation to developmental engineering. Bioact Mater. 2025;49 :418-436. doi: 10.1016/j.bioactmat.2025.03.009. PubMed PMID:40165829 PubMed Central PMC11957753.
  9. Liu, Y, Zhou, H, Pang, P, Liu, Y, Situ, J, Wang, J et al.. Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia. Stem Cell Res Ther. 2025;16 (1):161. doi: 10.1186/s13287-025-04219-3. PubMed PMID:40165226 PubMed Central PMC11959820.
  10. Ayati, A, Khodabandelu, S, Khaleghi, S, Nourmohammadi, A, Jafari, F, Ahmadianghalehsorkh, M et al.. A systematic review and network meta-analysis of the association between periodontitis and inflammatory bowel diseases. BMC Oral Health. 2025;25 (1):463. doi: 10.1186/s12903-025-05830-9. PubMed PMID:40165211 .
  11. Panchal, P, Rauwel, P, Sharma, S, Nehra, SP, Estephan, E, Praakle, K et al.. Ocimum tenuiflorum leaf-mediated graphitic carbon nitride and ZnO/GCN nanohybrid: a sustainable approach for environmental applications. Environ Sci Pollut Res Int. 2025; :. doi: 10.1007/s11356-025-36299-2. PubMed PMID:40164905 .
  12. Zhao, Y, Zhao, Y, Liang, L, Chen, A, Li, Y, Liu, K et al.. Human neuron chimeric mice reveal impairment of DVL-1-mediated neuronal migration by sevoflurane and potential treatment by rTMS. Exp Mol Med. 2025; :. doi: 10.1038/s12276-025-01425-0. PubMed PMID:40164685 .
  13. Mora, A, García-Bernal, D, Rodríguez-Lozano, FJ, Ghilotti, J, Lozano, A, López-García, S et al.. Biocompatibility and osteogenic potential of novel tricalcium silicate-based materials in human dental pulp stem cells: Advancing vital pulp therapies. Dent Mater. 2025; :. doi: 10.1016/j.dental.2025.03.011. PubMed PMID:40164523 .
  14. Li, L, Wang, Y, Hu, M. Dysregulation of lncRNA GATA3-AS1 is Involved in the Pathogenesis of Pulpitis by the Regulation of miR-17-3p. J Inflamm Res. 2025;18 :4459-4469. doi: 10.2147/JIR.S504048. PubMed PMID:40162083 PubMed Central PMC11955176.
  15. Hiraiwa, T, Yoshii, S, Kawada, J, Sugawara, T, Kawasaki, T, Shibata, S et al.. A human iPSC-Derived myelination model for investigating fetal brain injuries. Regen Ther. 2025;29 :100-107. doi: 10.1016/j.reth.2025.02.014. PubMed PMID:40162018 PubMed Central PMC11953958.
  16. Jalilvand, M, Khoshbin, E, Barabadi, Z, Karkehabadi, H, Sharifi, E. Fabrication and characterization of nanocomposite scaffold containing zinc-doped mesoporous bioglass: Evaluation of the antioxidant properties, hemocompatibility and proliferation of apical papilla stem cells. Bioimpacts. 2025;15 :30300. doi: 10.34172/bi.30300. PubMed PMID:40161949 PubMed Central PMC11954743.
  17. Vidotti, RB, Yoshikawa, AH, Sant'Ana, M, Souza, HR, Possebon, L, Navarro da Rocha, D et al.. Reduction of inflammation and improvement of skin tissue repair using biomaterials composed of hydroxyapatite and chitosan associated to conditioned media derived from dental pulp stem cells. Int J Biol Macromol. 2025; :142353. doi: 10.1016/j.ijbiomac.2025.142353. PubMed PMID:40158558 .
  18. Ouchi, T, Morikawa, S, Nakagawa, T, Asoda, S. Platelet-derived Growth Factor Receptor-α as a Biomarker for Tongue Spindle Cell Carcinoma. Anticancer Res. 2025;45 (4):1387-1393. doi: 10.21873/anticanres.17524. PubMed PMID:40155028 .
  19. Li, Y, Li, Q, Zhang, K, Wu, Y, Nuerlan, G, Wang, X et al.. Metabolic Rewiring and Post-Translational Modifications: Unlocking the Mechanisms of Bone Turnover in Osteoporosis. Aging Dis. 2025; :. doi: 10.14336/AD.2025.0123. PubMed PMID:40153585 .
  20. Palczewska-Komsa, M, Puszkarz, A, Dalewski, B, Kaczor-Wiankowska, K, Sobolewska, E, Pałka, Ł et al.. Analysis of selected parameters of reparative dentin after direct pulp capping with MTA Repair HP in human teeth, using CBCT and micro-CT. Dent Med Probl. 2025; :. doi: 10.17219/dmp/189747. PubMed PMID:40153267 .
  21. Zeng, J, Yang, Y, Jiang, C, Wu, B, Chen, M. An HRL-SC/HIF-1α positive feedback loop enhances cell proliferation, migration and angiogenesis in dental pulp stem cells via PI3K/AKT signalling pathway. Int Endod J. 2025; :. doi: 10.1111/iej.14229. PubMed PMID:40152548 .
  22. Franco-Arellanes, MC, Toledo-Valdes, PX, Díaz-Hernández, C, Díaz-Castillejos, R, García-Reyes, ED, Ramírez-Thomé, SK et al.. Expression of O-GlcNAcylation in pulp tissue and DPSCs of healthy dental organs. Folia Histochem Cytobiol. 2025; :. doi: 10.5603/fhc.103756. PubMed PMID:40152124 .
  23. Zhang, HJ, Ming, JJ, Zhang, HX, Fang, SY, Liu, QW, Zhang, HY et al.. A Comprehensive Review: Advances in Mesenchymal Stem Cell Applications for Burn Wound Repair. Stem Cells Int. 2025;2025 :6683745. doi: 10.1155/sci/6683745. PubMed PMID:40151391 PubMed Central PMC11949610.
  24. Zhao, K, Guo, Y, He, Y, Wu, Y, Hu, Z, Chi, X et al.. Targeting the PTN/PTPRZ1-ROS Pathway to Promote Bone Regeneration. Biomedicines. 2025;13 (3):. doi: 10.3390/biomedicines13030695. PubMed PMID:40149671 PubMed Central PMC11940355.
  25. Kumar, D, Pride, M, Mukherjee, K, Jain, G, Mutreja, I, Jones, RS et al.. The use of oxymetazoline-based nasal solutions to remove bacteria-blood debris and eradicate Rothia dentocariosa: an artificial cavity model study. BMC Oral Health. 2025;25 (1):448. doi: 10.1186/s12903-025-05791-z. PubMed PMID:40148918 PubMed Central PMC11951828.
  26. Rezaei, F, Shakoori, S, Fazlyab, M, Esnaashari, E, Savadkouhi, ST. Effect of low-level laser on proliferation, angiogenic and dentinogenic differentiation of human dental pulp stem cells. BMC Oral Health. 2025;25 (1):441. doi: 10.1186/s12903-025-05656-5. PubMed PMID:40148901 PubMed Central PMC11948823.
  27. Pamulang, YV, Oontawee, S, Rodprasert, W, Padeta, I, Sa-Ard-Lam, N, Mahanonda, R et al.. Potential upscaling protocol establishment and wound healing bioactivity screening of exosomes isolated from canine adipose-derived mesenchymal stem cells. Sci Rep. 2025;15 (1):10617. doi: 10.1038/s41598-025-93219-7. PubMed PMID:40148423 PubMed Central PMC11950392.
  28. Li, Z, Wan, M, Cui, D, Tian, Q, Li, Y, Yu, S et al.. DNMTi@ZIF-8 Enhances Biomimetic Pulp Regeneration via Epigenetic Regulation. J Dent Res. 2025; :220345251315468. doi: 10.1177/00220345251315468. PubMed PMID:40143798 .
  29. Almutairi, N, Alhussein, A, Alenizy, M, Ba-Armah, I, Alqarni, H, Oates, TW et al.. Novel Bioactive Resin Coating with Calcium Phosphate Nanoparticles for Antibacterial and Remineralization Abilities to Combat Tooth Root Caries. Int J Mol Sci. 2025;26 (6):. doi: 10.3390/ijms26062490. PubMed PMID:40141134 PubMed Central PMC11941978.
  30. Fang, F, Guo, X, Liu, S, Dang, L, Chen, Z, Yang, Y et al.. LincRNA-ASAO promotes dental pulp repair through interacting with PTBP1 to increase ALPL alternative splicing. Stem Cell Res Ther. 2025;16 (1):149. doi: 10.1186/s13287-025-04274-w. PubMed PMID:40140936 PubMed Central PMC11948687.
  31. Jaksic Karisik, M, Jović Orsini, N, Carkic, J, Lazarevic, M, Mitić, D, Jokanovic, B et al.. A Carbon-Based Nanomaterial with Dichotomous Effects: Antineoplastic on Oral Cancer Cells and Osteoinductive/Chondroinductive on Dental Pulp Stem Cells. J Funct Biomater. 2025;16 (3):. doi: 10.3390/jfb16030109. PubMed PMID:40137387 PubMed Central PMC11943258.
  32. Lin, HC, Chen, CS, Lin, KY, Huang, YL, Hsu, HH, Kuo, YL et al.. Designing Superhydrophilic 3D Porous Surfaces on Polyetherketoneketone Surfaces to Promote Biocompatibility. J Funct Biomater. 2025;16 (3):. doi: 10.3390/jfb16030106. PubMed PMID:40137385 PubMed Central PMC11943029.
  33. Leelasangsai, W, Thummachot, K, Thammasarnsophon, P, Srion, A, Suwanprateeb, J, Patntirapong, S et al.. Cobalt-Incorporated Hydroxyapatite Conditioned Media Promotes In Vitro Scratch Wound Healing and Mesenchymal Stem Cell Migration. J Funct Biomater. 2025;16 (3):. doi: 10.3390/jfb16030072. PubMed PMID:40137351 PubMed Central PMC11942815.
  34. Maria, MKM, Abdel Moniem, EM, Hanafy, AK, Farag, DBE, Radwan, IA, Abbass, MMS et al.. Age-Related Oral and Para-Oral Tissue Disorders: The Evolving Therapeutic and Diagnostic Potential of Exosomes. Dent J (Basel). 2025;13 (3):. doi: 10.3390/dj13030106. PubMed PMID:40136734 PubMed Central PMC11941486.
  35. Mekhemar, M, Terheyden, I, Dörfer, C, Fawzy El-Sayed, K. Inflammatory Modulation of Toll-like Receptors in Periodontal Ligament Stem Cells: Implications for Periodontal Therapy. Cells. 2025;14 (6):. doi: 10.3390/cells14060432. PubMed PMID:40136681 PubMed Central PMC11941712.
  36. Baďurová, B, Nystøl, K, Michalič, TO, Kucháriková, V, Statelová, D, Nováková, S et al.. Temporal Profiling of Cellular and Molecular Processes in Osteodifferentiation of Dental Pulp Stem Cells. Biology (Basel). 2025;14 (3):. doi: 10.3390/biology14030257. PubMed PMID:40136514 PubMed Central PMC11939960.
  37. Hu, S, Zheng, C, Jiang, P, Zhang, Q, Liu, Y, Dou, L et al.. 3D visualization of neurovascular networks in pulp-exposed rat molars using tissue clearing techniques. Odontology. 2025; :. doi: 10.1007/s10266-025-01092-7. PubMed PMID:40133600 .
  38. Hu, M, Fan, Z. Role and mechanisms of histone methylation in osteogenic/odontogenic differentiation of dental mesenchymal stem cells. Int J Oral Sci. 2025;17 (1):24. doi: 10.1038/s41368-025-00353-z. PubMed PMID:40133254 PubMed Central PMC11937254.
  39. Koike, H, Sugimura, M, Ouchi, R, Yoshimoto, Y, Manabe, I, Oishi, Y et al.. Macrophage Subpopulation Promotes Skeletal Muscle Regeneration Through HGF/MET Signaling-Mediated Skeletal Muscle Stem Cell Proliferation. Aging Cell. 2025; :e70042. doi: 10.1111/acel.70042. PubMed PMID:40132988 .
  40. Li, H, Yu, N, Li, X, Tang, X, Sun, Y, Si, C et al.. [Effects of cell area on single odontoblast polarization and differentiation via microarray technology]. Hua Xi Kou Qiang Yi Xue Za Zhi. 2025;43 (2):183-189. doi: 10.7518/hxkq.2025.2024392. PubMed PMID:40132963 PubMed Central PMC11960410.
  41. Wu, KY, Kearn, N, Truong, D, Choulakian, MY, Tran, SD. Advances in Regenerative Medicine, Cell Therapy, and 3D Bioprinting for Corneal, Oculoplastic, and Orbital Surgery. Adv Exp Med Biol. 2025; :. doi: 10.1007/5584_2025_855. PubMed PMID:40131704 .
  42. Wu, KY, Osman, RM, Esomchukwu, O, Marchand, M, Nguyen, BH, Tran, SD et al.. Advances in Regenerative Medicine, Cell Therapy, and 3D Bioprinting for Glaucoma and Retinal Diseases. Adv Exp Med Biol. 2025; :. doi: 10.1007/5584_2025_854. PubMed PMID:40131702 .
  43. Chen, J, Deng, L. KLF2 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Regulating Nrf2 Expression. Int Dent J. 2025;75 (3):1554-1563. doi: 10.1016/j.identj.2025.02.019. PubMed PMID:40121852 .
  44. Hu, M, Zhang, Q, Xu, J, Xu, L, Xu, X, Wang, J et al.. New considerations in selecting donors for dental pulp stem cells: a pilot study. Biomed Eng Online. 2025;24 (1):37. doi: 10.1186/s12938-025-01367-8. PubMed PMID:40119437 PubMed Central PMC11929365.
  45. Deng, P, Huang, J, Zhang, Q, Li, Y, Li, J. Correction to: The role of EMILIN-1 in the osteo/odontogenic differentiation of dental pulp stem cells. BMC Oral Health. 2025;25 (1):419. doi: 10.1186/s12903-025-05759-z. PubMed PMID:40119372 PubMed Central PMC11929322.
  46. Yang, J, Weng, X, Chen, C, Pan, Y. Notoginsenoside R1 Promotes Osteogenic Differentiation of Dental Pulp Stem Cells via MAPK Pathway. Discov Med. 2025;37 (194):486-495. doi: 10.24976/Discov.Med.202537194.40. PubMed PMID:40116096 .
  47. Kim, J, Lee, MC, Jeon, J, Rodríguez-delaRosa, A, Endo, Y, Kim, DS et al.. Combinational regenerative inductive effect of bio-adhesive hybrid hydrogels conjugated with hiPSC-derived myofibers and its derived EVs for volumetric muscle regeneration. Bioact Mater. 2025;43 :579-602. doi: 10.1016/j.bioactmat.2024.09.013. PubMed PMID:40115877 PubMed Central PMC11923440.
  48. Ying, LH, Abdullah, M, Fuad, NA, Seong, LG, Azami, NH, Noor, NSM et al.. Biocompatibility of irrigation solutions to dental-derived mesenchymal stem cells in regenerative endodontic procedure: a systematic review of in vitro studies. Odontology. 2025; :. doi: 10.1007/s10266-025-01087-4. PubMed PMID:40111730 .
  49. Zhong, J, Zhang, Y, Lin, S, Kang, J, Hu, M, Liu, J et al.. Activin a regulates vascular formation and stabilization in direct coculture of dental pulp stem cells and endothelial cells. Int Endod J. 2025; :. doi: 10.1111/iej.14226. PubMed PMID:40106315 .
  50. Hermans, F, Vankelecom, H, Bronckaers, A, Lambrichts, I. Establishment of 3D Tooth Organoid Culture from Early-Postnatal Mouse Molar and Incisor. Methods Mol Biol. 2025; :. doi: 10.1007/7651_2025_623. PubMed PMID:40106152 .
  51. Belyaeva, A, Perepelina, K, Kuznetsova, E, Smirnova, D, Yakovleva, T, Turilova, V et al.. Generation of iPSCs line from patient with Singleton-Merten syndrome. Hum Cell. 2025;38 (3):71. doi: 10.1007/s13577-025-01203-0. PubMed PMID:40106038 .
  52. Santos, AGD, Spigariol, KS, Santos, LM, Holzhausen, M, Sipert, CR. Immunomodulatory effects of apical papilla cells on periodontal ligament fibroblasts stimulated with Escherichia coli lipopolysaccharide: an in vitro study. J Appl Oral Sci. 2025;33 :e20240338. doi: 10.1590/1678-7757-2024-0338. PubMed PMID:40105577 PubMed Central PMC11869941.
  53. Li, X, Xia, Y, Wang, Z, Yin, Z, Weng, M, Tian, F et al.. Three-dimensional matrix stiffness-based stem cell soil: Tri-phase biomechanical structure promoted human dental pulp stem cells to achieve pulpodentin regeneration. Mater Today Bio. 2025;31 :101591. doi: 10.1016/j.mtbio.2025.101591. PubMed PMID:40104646 PubMed Central PMC11919457.
  54. Rewthamrongsris, P, Phothichailert, S, Chokechanachaisakul, U, Janjarussakul, P, Kornsuthisopon, C, Samaranayake, L et al.. Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla. BMC Oral Health. 2025;25 (1):398. doi: 10.1186/s12903-025-05721-z. PubMed PMID:40102842 PubMed Central PMC11917056.
  55. Emad, M, Alnatour, M, Alshaer, W, Gibbs, JL, Michot, B, Alqudah, D et al.. Impact of hydroxyapatite nanoparticles on the cellular processes of stem cells derived from dental tissue sources. Cell Tissue Res. 2025; :. doi: 10.1007/s00441-025-03962-6. PubMed PMID:40100346 .
  56. Qiu, Y, Zhao, Y, Jia, L, Xiao, H, Sun, S, Gu, W et al.. Combination of dasatinib and quercetin promotes osteogenic differentiation and stemness maintenance of hPDLSCs via YAP/TAZ. Anim Cells Syst (Seoul). 2025;29 (1):19-29. doi: 10.1080/19768354.2025.2477050. PubMed PMID:40098711 PubMed Central PMC11912249.
  57. Cho, J, Park, JJ, Seo, E, Lee, OH, Cho, TJ, Kim, JY et al.. Self-Assembled Organoid-Tissue Modules for Scalable Organoid Engineering: Application to Chondrogenic Regeneration. Acta Biomater. 2025; :. doi: 10.1016/j.actbio.2025.03.028. PubMed PMID:40097127 .
  58. Ayyildiz, BG, Kocak, A, Bozoglan, E. The Comparison of Osteogenic Differentiation of Anodized Gradually and Non-Gradually Novel Implant Surfaces by 3D Cell Culture: An In Vitro Study. Int J Oral Maxillofac Implants. 2025;0 (0):1-31. doi: 10.11607/jomi.11079. PubMed PMID:40096517 .
  59. Manoharan, I, Jeya Goutham, PA, Kalaivani, M, Madhavan, H, Balaji, D, K, S et al.. Comparative Evaluation of the Effects of Calcium Hydroxide Intracanal Medicament and Antibiotic Paste on Dentin Microhardness: A Systematic Review. Cureus. 2025;17 (2):e78886. doi: 10.7759/cureus.78886. PubMed PMID:40091937 PubMed Central PMC11907672.
  60. Zhang, X, Yang, W, Zhu, B, Su, L, Li, H. Photobiomodulation therapy facilitates transplantation of dental pulp stem cells for spinal cord injury. Photodiagnosis Photodyn Ther. 2025; :104559. doi: 10.1016/j.pdpdt.2025.104559. PubMed PMID:40090474 .
  61. Sekar, Y, Ishwar, D, Tan, B, Venkatakrishnan, K. Nano biosensor unlocks tumor derived immune signals for the early detection of ovarian cancer. Biosens Bioelectron. 2025;278 :117368. doi: 10.1016/j.bios.2025.117368. PubMed PMID:40088704 .
  62. Yu, A, Yoon, D, An, HB, Choi, U, Heo, HR, Chae, DH et al.. The regulatory role of ACP5 in the diesel exhaust particle-induced AHR inflammatory signaling pathway in a human bronchial epithelial cell line. Sci Rep. 2025;15 (1):8826. doi: 10.1038/s41598-024-84280-9. PubMed PMID:40087344 PubMed Central PMC11909186.
  63. Suwittayarak, R, Klincumhom, N, Phrueksotsai, C, Limjeerajarus, N, Limjeerajarus, CN, Egusa, H et al.. Shear stress preconditioning enhances periodontal ligament stem cell survival. Arch Oral Biol. 2025;173 :106232. doi: 10.1016/j.archoralbio.2025.106232. PubMed PMID:40086040 .
  64. Pereira, JA, Martin, V, Araújo, R, Grenho, L, Gomes, P, Marto, J et al.. Morin-Loaded Chitosan-Poloxamer Hydrogel as an Osteoinductive Delivery System for Endodontic Applications. J Biomed Mater Res A. 2025;113 (3):e37895. doi: 10.1002/jbm.a.37895. PubMed PMID:40084515 .
  65. Elahi, A, Duncan, W, Li, KC, Bhattacharjee, T, Coates, D. Supercritical CO2 With Enzymatic Posttreatment Enhances Mechanical and Biological Properties of Cancellous Bovine Bone Block Grafts. J Biomed Mater Res A. 2025;113 (3):e37896. doi: 10.1002/jbm.a.37896. PubMed PMID:40084482 .
  66. Sui, M, Lyu, J, Zhou, J, Liao, Q, Xiao, Z, Jin, M et al.. Circ-AARS plays an important role during the odontogenic differentiation of dental pulp stem cells by modulating miR-24-3p/KLF6 expression. Stem Cell Res Ther. 2025;16 (1):137. doi: 10.1186/s13287-025-04239-z. PubMed PMID:40083007 PubMed Central PMC11907881.
  67. Soleymani, AA, Biria, M, Torshabi, M, Mozaffari, N. Cytotoxicity and proliferation effects of cold ceramic on stem cells from human exfoliated deciduous teeth compared to MTA: an in vitro study. BMC Oral Health. 2025;25 (1):377. doi: 10.1186/s12903-025-05756-2. PubMed PMID:40082877 PubMed Central PMC11908088.
  68. Ono, M, Tosa, I, Dang, AT, Wang, Z, Kimura, M, Kitagawa, W et al.. BMP-2 generates a functional bone marrow niche by inducing the differentiation of local mesenchymal cells into CAR cells. Blood Adv. 2025; :. doi: 10.1182/bloodadvances.2024014062. PubMed PMID:40080674 .
  69. Lu, H, Shi, F, Wang, B, Zheng, Y, Lu, J, Zeng, B et al.. Molecular Biological Comparison of Pulp Stem Cells from Supernumerary Teeth, Permanent Teeth, and Deciduous Teeth for Endodontic Regeneration. Int J Mol Sci. 2025;26 (5):. doi: 10.3390/ijms26051933. PubMed PMID:40076559 PubMed Central PMC11901064.
  70. Dawood, RM, Mahdee, AF. Inducing Osteogenesis in Human Pulp Stem Cells Cultured on Nano-Hydroxyapatite and Naringin-Coated 3D-Printed Poly Lactic Acid Scaffolds. Polymers (Basel). 2025;17 (5):. doi: 10.3390/polym17050596. PubMed PMID:40076089 PubMed Central PMC11902540.
  71. Saskianti, T, Angelina, M, Dewi, AM, Antonius, Y, Zahri, AN, Ridwan, RD et al.. Osteogenesis Potential of Polymethylmethacrylate-Hydroxyapatite and Stem Cells from Human Exfoliated Deciduous Teeth as Alveolar Bone Graft: An In Silico Study. Eur J Dent. 2025; :. doi: 10.1055/s-0044-1801280. PubMed PMID:40073999 .
  72. Radi, NA, Habba, DA, Hallool, SI, Almeshari, AA, Abd Elsamia, HM. Evaluation of Regeneration Potential of Bone Marrow-Derived Mesenchymal Stem Cells on Induced Damaged Submandibular Salivary Gland in Mice. Eur J Dent. 2025; :. doi: 10.1055/s-0044-1791940. PubMed PMID:40073996 .
  73. Luo, L, Xing, Z, Li, Y, Wang, B, Dong, N, Sun, J et al.. Injective hydrogel encapsulating dental pulp stem cells for the treatment of traumatic optic nerve injury. Front Bioeng Biotechnol. 2025;13 :1528749. doi: 10.3389/fbioe.2025.1528749. PubMed PMID:40070549 PubMed Central PMC11893850.
  74. Fakhr, MJ, Farsani, ME, Fath-Bayati, L, Seyedebrahimi, R, Sadrjahani, M, Kavakebian, F et al.. Development and evaluation of BDNF-loaded PCL/PVA two-layer nerve guidance conduit with enhanced biomechanical and biological properties for peripheral nerve regeneration. Heliyon. 2025;11 (4):e42792. doi: 10.1016/j.heliyon.2025.e42792. PubMed PMID:40066039 PubMed Central PMC11891681.
  75. Xu, X, Zhang, Z, Tian, W, Cao, M, Wang, Z, Li, F et al.. Melatonin Increased Autophagy Level to Facilitate Osteogenesis of Inflamed PDLSCs Through TMEM110 Signaling Pathways. J Pineal Res. 2025;77 (2):e70039. doi: 10.1111/jpi.70039. PubMed PMID:40065592 PubMed Central PMC11894363.
  76. Ouyang, M, Yu, X, Zhong, J, Mao, Y, Cui, Y, Jiang, H et al.. Injectable sodium alginate/4-arm polyethylene glycol-lipoic acid double-network hydrogel loading Ca2+-tannic acid nanocomposite treats periodontitis via anti-bacteria, ROS scavenging and osteogenesis. Int J Biol Macromol. 2025;307 (Pt 1):141841. doi: 10.1016/j.ijbiomac.2025.141841. PubMed PMID:40064278 .
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